Do you spend a lot of time on your feet? If so, an anti-fatigue mat might be just what you need. Anti-fatigue mats are designed to help a person who is working in a standing position for prolonged periods of time. Most anti-fatigue matting is a combination of an ergonomic pattern and a cushioning underlay. The cushioning causes constant subconscious balance checks and micro-movements that stimulate blood flow through the legs and lower extremities.